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The 28th Annual Meeting of KSBNS K-Brain 2025 &
The 3rd CJK Neuroscience Meeting K-Brain 2025 &
The 3rd CJK Neuroscience Meeting

  • Date

    Aug 24(Sun) – Aug 27(Wed), 2025

  • Venue

    Songdo Convensia, Incheon, Korea

Symposium

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  • August 24 (Sun)
    13:00-14:55
    Symposium 01. Molecular and circuit-level understanding of memory and memory related disorders
    Grand Ballroom
  • This symposium focuses on the molecular and circuit-level understanding of memory and its related disorders. It will explore the synaptic and circuit mechanisms involved in cognitive and behavioral processes such as attention, learning and memory, fear, reward, working memory, and decision-making, as well as the role of these mechanisms in memory-related disorders. The aim is to provide new insights and methods for the treatment of these disorders, which is of great significance to researchers and clinicians alike.
  • Organizer
    Weidong Li (Shanghai Jiao Tong University)
    Ain Chung (Korea Advanced Institute of Science and Technology)
  • Moderator
    Weidong Li (Shanghai Jiao Tong University)
  • Speaker

    Epigenetic and engram mechanisms in remote memory dysfunction   
    Weidong Li (Shanghai Jiao Tong University)

    Hippocampal cellular and molecular representations of fear memory reconsolidation and extinction   
    Satoshi Kida (The University of Tokyo)

    Two orthogonal ensembles encoding of engram in the dentate gyrus   
    Yi Zhong (Tsinghua University)

    Septal GABAergic neurons switch memories to enable update   
    Jin-Hee Han (Korea Advanced Institute of Science and Technology)

    Exploring the impact of cognitive training on hippocampal synaptic circuit function   
    Ain Chung (Korea Advanced Institute of Science and Technology)

    Serpina1e mediates the exercise-induced enhancement of hippocampal memory   
    Hyunyoung Kim (Korea Brain Research Institute)

  • August 24 (Sun)
    13:00-14:55
    Symposium 02. Mechanotransduction in the peripheral and central nerve system
    Premier Ballroom A
  • Mechanically activated ion channels convert mechanical forces into electrical signals in the nerve system. In this symposium, the invited speakers will present their latest research showcasing the diverse physiological roles of mechanically activated ion channels in the peripheral sensory neurons for the sense of touch, mechanical pain, proprioception and in the central nerve system for maintaining brain homeostasis, as well as the continued effort for cloning novel mechanically activated ion channels.
  • Organizer
    Bailong Xiao (Tsinghua University)
    Uhtaek Oh (Korea Institute of Science and Technology)
  • Moderator
    Bailong Xiao (Tsinghua University)
    Uhtaek Oh (Korea Institute of Science and Technology)
  • Speaker

    Molecular and physiological functions of a mechanically activated ion channel, Tentonin 3   
    Uhtaek Oh (Korea Institute of Science and Technology)

    Structure-function and physiological roles of mechanically activated PIEZO channels   
    Bailong Xiao (Tsinghua University)

    ATP release in physiology and pathology: A mechanobiological perspective   
    Masahiro Sokabe (Kanazawa Institute of Technology)

    Identification of the brain-to-spinal opioidergic circuits driving tactile pain   
    Longzhen Cheng (Southern University of Science and Technology)

    Mechanically evoked ATP release from Merkel cells mediates non-neuronal paracrine signaling   
    Young Min Bae (Konkuk University)

  • August 24 (Sun)
    13:00-14:55
    Symposium 03. Neuroglia in diseases of cognition
    Premier Ballroom B
  • This symposium will delve into the diverse roles of glial cells in cognitive disorders. Topics include astrocyte atrophy and asthenia and their contributions to cognitive decline, microglial dysfunction and therapeutic strategies targeting gap junctions: connexin43, and the involvement of oligodendroglial precursor cells in neuropsychiatric disorders. The symposium will also address dysfunctional astrocyte signaling in cognitive inflexibility and explore the role of ependymoglial cells in regulating the cerebrospinal fluid-periphery barrier and its impact on cognition. The symposium will provide a platform to explore how neuroglial malfunction contributes to cognitive disorders and highlight potential therapeutic targets. By integrating current research on glial cell roles in cognitive disorders, the event aims to inspire new strategies for treatment, fostering innovative approaches to managing cognitive impairments and related conditions.
  • Organizer
    Chenju Yi (The Seventh Affiliated Hospital of Sun Yat-sen University)
    Alexei Verkhratsky (University of Manchester)
  • Co-organizer
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  • Moderator
    Chenju Yi (The Seventh Affiliated Hospital of Sun Yat-sen University)
  • Speaker

    Astrocyte atrophy and asthenia lead pathophysiology of cognitive disorders   
    Alexej Verkhratsky (University of Manchester)

    Turning microglia neuroprotective: towards connexin43-specific therapy of Alzheimer’s disease   
    Chenju Yi (The Seventh Affiliated Hospital of Sun Yat-sen University)

    Dysfunctional astrocyte signaling in cognitive inflexibility   
    Jun Nagai (RIKEN)

    Suppression of microglial Cx43 hemichannel promotes short-term and long-term recovery from traumatic brain injury   
    Yixun Su (Sun Yat-sen University)

    Ependymoglial CSF-periphery gate in health and disease   
    Baoman Li (China Medical University)

    Excitatory neuronal ERBB4 drives early pathophysiology of Alzheimer’s disease   
    Se Young Lee (Korea Advanced Institute of Science and Technology)

  • August 24 (Sun)
    13:00-14:55
    Symposium 04. Novel insights in sleep regulation and function
    Premier Ballroom C
  • The symposium aims to explore the latest advancements in the understanding of sleep regulation and its multifaceted functions, particularly memory processing during sleep. Sleep is a critical biological process that affects physical health, cognitive performance, and emotional well-being. Recent research has unveiled novel mechanisms underlying sleep regulation. This symposium will bring together leading experts in all three CJK countries in the field to share their findings from studies in animal models and humans, discuss innovative methodologies, and identify future directions for research.
  • Organizer
    Min Xu (Chinese Academy of Sciences)
    Thomas McHugh (RIKEN)
  • Moderator
    Min Xu (Chinese Academy of Sciences)
    Thomas McHugh (RIKEN)
  • Speaker

    Circuit mechanisms of hippocampal memory processing during sleep   
    Thomas McHugh (RIKEN)

    Neuromodulator control of hippocampal-dependent memory processing during sleep   
    Min Xu (Chinese Academy of Sciences)

    Indigenous herb TCU410 mitigates memory impairment in sleep-deprived and triple transgenic Alzheimer's disease mice   
    Peeraporn Varinthra (Tzu Chi University)

    Mechanisms underlying the regulation of sleep homeostasis: exploring key signaling pathways   
    Staci Jakyong Kim (Korea Advanced Institute of Science and Technology)

    Synaptic regulation in sleep homeostasis   
    Shoi Shi (University of Tsukuba)

    Memory editing during sleep in human   
    XiaoQing Hu (The University of Hong Kong)

  • August 24 (Sun)
    13:00-14:55
    Symposium 05. The brainstem: a critical conduit for body-brain signaling
    Rm.113-115
  • The brainstem serves as a pivotal hub for integrating peripheral sensory inputs and orchestrating central nervous system responses, yet its functional significance in body-brain signaling remains underexplored. This symposium will highlight cutting-edge research uncovering novel neural pathways and mechanisms by which the brainstem regulates behaviors critical for homeostasis, such as ingestive behavior. Four distinguished speakers will present recent discoveries, utilizing state-of-the-art techniques such as optogenetics, calcium imaging, and circuit mapping, to unravel how the brainstem bridges physiological states with adaptive responses. This symposium offers a compelling narrative that will captivate a diverse audience interested in neuroscience, physiology, and translational medicine.
  • Organizer
    Sung-Yon Kim (Seoul National University)
    Cheng Zhan (University of Science and Technology of China)
  • Moderator
    Yu Fu (Agency for Science Technology and Research)
  • Speaker

    A pharynx-to-forebrain circuit for rapid thirst quenching   
    Sung-Yon Kim (Seoul National University)

    Brainstem catecholaminergic/NPY neurons: pivotal players in orchestrating energy intake and expenditure   
    Cheng Zhan (University of Science and Technology of China)

    Parallel gut-to-brain pathways orchestrate feeding behaviors   
    Ling Bai (Chinese Institute for Brain Research)

    NTS catecholamine neurons mediate hypoglycemic hunger via medial hypothalamic feeding pathways   
    Deniz Atasoy (University of Iowa)

    Brainstem opioid peptidergic neurons regulate cough reflexes in mice   
    Peng Cao (National Institute of Biological Sciences)

    Hypothalamic endothelial Notch suppression drives obesity-associated impairment of glucose uptake and insulin signaling   
    Yiyi Zhu (Sun Yat-sen University)

  • August 24 (Sun)
    13:00-14:55
    Symposium 06. [KSBNS-KSA Joint Symposium] Exploring the neuroscience of general anesthesia
    Rm.116-118
  • General anesthesia is one of the greatest achievements in human medicine, allowing millions of patients to safely undergo complex surgical and diagnostic procedures each year. Despite its widespread use, the mechanisms of action and effects of general anesthesia on the brain remain poorly understood. This symposium will explore the profound effects of general anesthesia on the brain and investigate underlying mechanisms. Experts in neuroscience and anesthesiology will present cutting-edge research, share valuable insights, and foster interdisciplinary collaboration. Attendees will gain a deeper understanding of the neuroscientific foundations of anesthesia and its implications for clinical practice.
  • Organizer
    Soo-Jin Oh (Korea Institute of Science and Technology)
  • Moderator
    Woosuk Chung (Chungnam National University)
    Soo-Jin Oh (Korea Institute of Science and Technology)
  • Speaker

    Brain network mechanisms of consciousness loss and recovery in general anesthesia   
    UnCheol Lee (University of Michigan)

    Anesthesia-induced neuroprotection against perioperative stroke, is it possible?   
    Woosuk Chung (Chungnam National University)

    predictive biomarker for postoperative delirium status after spinal surgery   
    Bon-Nyeo Koo (Yonsei University)

    Understanding postoperative cognitive dysfunction: clinical concepts and mechanisms   
    Jin-Young Hwang (SMG-SNU Boramae Medical Center)

    Role of astrocytes in general anesthesia and postoperative cognitive dysfunction   
    Soo-Jin Oh (Korea Institute of Science and Technology)

  • August 25 (Mon)
    08:30-10:25
    Symposium 07. Neuromodulation in psychiatry: from circuit to psychopharmacology
    Grand Ballroom
  • The symposium "Neuromodulation in Psychiatry: From Circuit to Psychopharmacology" gathers leading experts to delve into innovative neuromodulation techniques for treating psychiatric disorders, with a focus on both mechanistic insights and therapeutic advancements. Under the leadership of Chair Ti-Fei Yuan from Shanghai Jiaotong University and Co-Chair Ji Hu from ShanghaiTech University, the session highlights cutting-edge interventions for treatment-resistant depression and beyond. This symposium offers a comprehensive and interdisciplinary exploration of the latest neuromodulatory approaches, appealing to a diverse audience of neuroscientists, clinicians, and pharmacologists interested in the forefront of psychiatric innovation.
  • Organizer
    Tifei Yuan (Shanghai Mental Health Center)
    Ji Hu (ShanghaiTech University)
  • Moderator
    Tifei Yuan (Shanghai Mental Health Center)
  • Speaker

    Maintenance repetitive transcranial magnetic stimulation for depression: A randomized clinical trial   
    Yoshihiro Noda (Keio University)

    Transcranial pulse stimulation for depression – a new kid on the block   
    Georg Kranz (Hong Kong Polytechnic University)

    Brain mechanisms of excitatory transcranial magnetic stimulation for treatment-resistant depression   
    Cheng-Ta Li (National Yang-Ming Chiao-Tung University)

    Targeting protein complexes as therapeutic targets for the treatment of neuropsychiatric diseases   
    Fang Liu (University of Toronto)

    Neural-immune communication   
    Ji Hu (ShanghaiTech University)

    Rethinking depression: cannabinoid-inspired targets without the legal baggage   
    Elisha Ab Rashid (Monash University Malaysia)

  • August 25 (Mon)
    08:30-10:25
    Symposium 08. Gene delivery to the brain: applications in life sciences and gene therapy
    Premier Ballroom C
  • In recent years, the rapid advancement of gene transfer technologies has been driven by the development of various cell-type-specific promoters/enhancers and transfer cargos, including lipid nanoparticles, AAV vectors, lentiviral vectors, and rabies virus vectors. By actively integrating these cutting-edge viral gene transfer technologies, neuroscientists can achieve groundbreaking discoveries at the forefront of global scientific research. This symposium brings together researchers developing viral vectors and lipid nanoparticles, as well as those utilizing them in their studies, to showcase the latest advancements in gene delivery techniques in neuroscience. Additionally, it will highlight cutting-edge neuroscience research that leverages these innovative technologies.
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  • Organizer
    Hirokazu Hirai (Gunma University)
  • Moderator
    Hirokazu Hirai (Gunma University)
  • Speaker

    Structural Analysis of Neural Networks Using High-Expression Adeno-Associated Virus Vectors   
    Hiroyuki Hioki (Juntendo University)

    Micro-dissection of the connectivity of cerebellar input layer with GABRA6 promotor by exploiting dispersed developmental time of granule cells and computational modeling   
    Taegon Kim (Korea Institute of Science and Technology)

    Long-term activity imaging of a neuronal population that sends input to a specific type of neurons via a low cytotoxic G-deleted rabies virus vector   
    Ken-ichi Inoue (Kyoto University)

    Modulation of gene expression and signaling cascade in mice brain exposed to nano-neonicotinoid pesticides   
    Dhanshree Borkar (National Forensic Sciences University)

    Nanoparticle-mediated gene delivery to enhance microglial phagocytosis for Alzheimer's disease therapy   
    Dong Woon Kim (Kyung Hee University)

    Highly specific and efficient AAV vectors targeting cortical GABAergic neurons   
    Yuuki Fukai (Gunma University)

  • August 25 (Mon)
    08:30-10:25
    Symposium 09. [KSBNS-KSNS Joint Symposium] Translational and clinical neuroscience: precision convergent medicine for treating intractable diseases, pain, and central nervous system trauma
    Rm.116-118
  • Recent advances in translational neuroscience have revolutionized our approach to treating central nervous system injuries and disorders. This symposium brings together leading experts to showcase cutting-edge therapeutic strategies that bridge laboratory innovations with clinical applications. Presentations will highlight novel delivery platforms including nanotechnology-enabled extracellular vesicles, targeted siRNA systems, and bioactive hydrogels for neural repair. The symposium will explore how these advanced therapeutic approaches, combined with insights from non-human primate models and clinical perspectives on neuropathic pain, are transforming treatment paradigms. Speakers will demonstrate how molecular and cellular interventions can be effectively translated into clinical solutions, offering new hope for patients with CNS injuries. This integrative approach, spanning from molecular mechanisms to clinical implementation, will provide valuable insights for researchers and clinicians across the neuroscience community.
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  • Organizer
    Inbo Han (CHA University)
    KiBum Lee (Rutgers, The State University of New Jersey)
  • Moderator
    Inbo Han (CHA University)
    KiBum Lee (Rutgers, The State University of New Jersey)
  • Speaker

    Transforming CNS injury therapeutics using a novel nanotechnology-enabled extracellular vesicle platform   
    KiBum Lee (Rutgers, The State University of New Jersey)

    Axon guidance gene-targeted siRNA delivery system improves neural stem cell transplantation therapy after spinal cord injury   
    Seil Sohn (CHA University)

    Current perspectives on neuropathic pain   
    Junseok Hur (Korea University)

    Advancing non-human primate disease models for superior translational research and enhanced clinical applicability   
    Seongjun Ryu (Eulji University)

    Multimodal therapy strategy based on a bioactive hydrogel for repair of spinal cord injury   
    Inbo Han (CHA University)

    C-reactive protein and unruptured intracranial aneurysm risk in Indonesia: a mendelian randomization study with real-world hospital-based study   
    Elvan Wiyarta (University of Indonesia Hospital)

  • August 25 (Mon)
    08:30-10:25
    Symposium 10. Synaptic balance in memory, homeostasis, and network stability
    Rm.204-205
  • Understanding the intricate interplay between synaptic transmission and neural circuits is essential for unraveling the complexities of brain function in both health and disease. This symposium brings together leading neuroscientists to present cutting-edge research, showcasing how synaptic and circuit mechanisms contribute to normal brain activity and how their dysregulation leads to neurological disorders. The topics span developmental plasticity, sensory processing, and pathological hyperexcitability, providing a comprehensive view of this rapidly evolving field. This session will provide a platform for discussing innovative approaches and integrative perspectives, bridging molecular, cellular, and circuit-level insights to advance our understanding of brain function and its dysregulation in disease.
  • Organizer
    Jong-Cheol Rah (Korea Brain Research Institute)
  • Moderator
    Chul-Hoon Kim (Yonsei University)
  • Speaker

    Synaptic input-selective homeostasis safeguards developing cortical neurons toward set-point activity   
    Mingshan Xue (Baylor College of Medicine)

    Cortico-hippocampal circuit interactions in shaping plasticity and memory functions   
    Jayeeta Basu (New York University)

    Disentangling morphological and synaptic mechanisms underlying network hyperexcitability in seizure disorders caused by mTOR hyperactivation   
    Matthew Weston (Virginia Tech)

    Acetylcholine switches the frequency-dependent activity filtering of thalamofrontal synapses   
    Jong-Cheol Rah (Korea Brain Research Institute)

    Systems consolidation involves reorganization of hippocampal engram circuits   
    Sangyoon Ko (University of Toronto)

  • August 25 (Mon)
    08:30-10:25
    Symposium 11. Neural codes across sensory systems: insights into perception and behavior
    Rm.107-109
  • Understanding how the brain encodes sensory information into neural signals and processes them to guide adaptive behavior remains a fundamental challenge in neuroscience. This symposium will focus on neural codes—spatiotemporal patterns of neural activity in neurons that represent, transmit, and process sensory information—and their distinct and multiplexed nature across sensory systems, including the visual, somatosensory, and olfactory systems. It will also explore how these sensory neural codes are used and integrated to shape perception, spatial cognition, and behavior. Topics will include the emergence of behaviorally relevant neural codes in the primary somatosensory cortex, olfactory neural codes associated with sensory-driven behaviors, the impact of neural code variability in the primary visual cortex on visual perception, and egocentric neural coding of space in the retrosplenial cortex that guides goal-directed navigation. Together, this symposium aims to advance our understanding of the neural coding and computational principles underlying sensory processing and reveal how neural codes create perceptions and drive adaptive behaviors.
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  • Organizer
    Jeehyun Kwag (Seoul National University)
  • Moderator
    Jeehyun Kwag (Seoul National University)
  • Speaker

    Stimulus information guides the emergence of behavior-related signals in primary somatosensory cortex during learning   
    Michael M. Kohl (University of Glasgow)

    Decoding olfactory bulb output: a behavioural assessment of rate, synchrony, and respiratory phase coding   
    Izumi Fukunaga (Okinawa Institute of Science and Technology)

    Neural variability structure in primary visual cortex is optimized for robust representation of perceptual similarity   
    Hyeyoung Shin (Seoul National University)

    Egocentric neural coding of space in the retrosplenial cortex guides goal-directed navigation   
    Jeehyun Kwag (Seoul National University)

    Functional synchronization of the intermediate hippocampus and medial prefrontal cortex after learning spatial navigation in VR space   
    Heung-Yeol Lim (Seoul National University)

  • August 25 (Mon)
    10:35-12:30
    Symposium 12. Diverse aspects of social behaviors: recognition, remembering, and reacting
    Premier Ballroom A
  • Social behaviors encompass a wide range of processes, including the ability to recognize oneself and others—an essential function for survival and social interactions in animals. The recognition of others is crucial for guiding appropriate behavioral responses such as fleeing, fighting, or mating.
    This symposium will explore the cellular and circuit mechanisms underlying these diverse social behaviors, covering key topics such as self-recognition (Takashi Kitamura, UTSW, USA), memory of others (Teruhiro Okuyama, University of Tokyo, Japan), aggression (Aki Takahashi, University of Tsukuba, Japan), and sex behaviors and social affiliative impairments in neurodevelopmental disorders (Ying Li, CIBR, China). Renowned researchers from China, Japan, and the USA will present their latest findings—both published and unpublished—offering valuable insights into the neural basis of social behaviors in both healthy and diseased states. This symposium will appeal to a broad audience, including those studying social behaviors, learning and memory, and reward-related processes, fostering interdisciplinary discussions and new research perspectives.
  • Organizer
    Yong-Seok Lee (Seoul National University)
    Takashi Kitamura (University of Texas Southwestern Medical Center)
  • Moderator
    Takashi Kitamura (University of Texas Southwestern Medical Center)
    Yong-Seok Lee (Seoul National University)
  • Speaker

    Social memory representation in the hippocampus   
    Teruhiro Okuyama (The University of Tokyo)

    Social and neural drivers of aggressive arousal and escalation of aggressive behavior   
    Aki Takahashi (University of Tsukuba)

    Starved yet social: decoding why worms aggregate and swarm on food, instead of dispersing   
    Navneet Shahi (Indian Institute of Science)

    Behavioral and dopaminergic signatures of social affiliative impairments in autistic juveniles   
    Ying Li (Chinese Institute for Brain Research)

    Egocentric coding of social, object and spatial geometry in the anterior cingulate cortex   
    Takashi Kitamura (University of Texas Southwestern Medical Center)

  • August 25 (Mon)
    10:35-12:30
    Symposium 13. Synapse function and diseases
    Premier Ballroom B
  • Synapse is critical for the formation of neuronal circuitry and brain functions, such as learning and memory. Abnormal formation of synapses is believed to contribute to a number of brain disorders, including epilepsy, autism and etc. The molecular mechanism governing the formation of synapse and its rules in diseases have not been fully understood. In this proposed symposium, we bring together scientists from China, Japan and Korea to share their discoveries on the mechanism of synapse formation and function, how synaptic plasticity contributes to learning and memory consolidation, transsynaptic mechanism of inhibition, as well as provide insights to understanding disease mechanisms that related to synapses. Since synapse is central to neuronal function, we believe the content of this symposium will be of interest to the audience of the conference.
  • Organizer
    Jun Xia (Hong Kong University of Science and Technology)
  • Moderator
    Jun Xia (Hong Kong University of Science and Technology)
  • Speaker

    Synaptic RNA localisation and protein compositions in focal epilepsy   
    Julie Qiaojin Lin (Hong Kong University of Science and Technology)

    Synaptic plasticity and memory dynamics   
    Akihiro Goto (Kyoto University)

    Temporal dynamics of synapse remodeling, gliosis, and lipidomic alterations in seizure evolution of a mouse model of west syndrome   
    Kihoon Han (Korea University)

    Transsynaptic mechanisms of synaptic inhibition   
    Jaewon Ko (Daegu Gyeongbuk Institute of Science and Technology)

    Role of novel neuroligin-2 associated protein in inhibitory synapse formation and function   
    Jun Xia (Hong Kong University of Science and Technology)

  • August 25 (Mon)
    10:35-12:30
    Symposium 14. Decoding the cerebellum in health and disease
    Premier Ballroom C
  • Recent progress in cerebellar research has revealed the role of the cerebellum not only in the classical sensorimotor processing but also in cognitive functions, and thus, dysfunction of the cerebellum leads to various neurodevelopmental and neurodegenerative disorders. Therefore, there is growing interest in the role of the cerebellum in diverse brain functions and its underlying neural mechanisms. In this symposium, we will introduce the cutting-edge researches by four globally renowned cerebellar researchers, and discuss our current understanding of cerebellar functions and future directions of the cerebellar research.
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  • Organizer
    Kazuo Kitamura (University of Yamanashi)
  • Moderator
    Kazuo Kitamura (University of Yamanashi)
  • Speaker

    Targeting the Cerebellum to Improve Parkinson’s Disease Motor Deficits: Mechanisms and Clinical Implications   
    Jing-Ning Zhu (Nanjing University)

    A cerebellar internal model for temporal prediction of rhythms   
    Masaki Tanaka (Hokkaido University)

    Temporal dynamics of Purkinje cell-intrinsic excitability govern cerebellar systems consolidation   
    Sang Jeong Kim (Seoul National University)

    Cerebellar Purkinje cell firing alterations contributes to aging-related declining motor coordination in mice   
    Alanna Watt (Mcgill University)

  • August 25 (Mon)
    10:35-12:30
    Symposium 15. [KSBNS-AKN Symposium] Integrative approaches to neurodegeneration: insights from multiomics, inflammation, and cellular pathways
    Rm.113-115
  • The symposium explores novel mechanisms underlying neurodegenerative diseases through the integration of multiomics data, neuroinflammatory pathways, and cellular organelle dysfunction. It highlights cutting-edge approaches to understanding aging, Parkinson's disease, ALS, FTD, and Lewy body disorders, emphasizing the interconnected roles of mitochondria, lysosomes, proteostasis, and inflammation in neurons and glial cells.
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  • Organizer
    Alexa Woo (Case Western Reserve University)
  • Supported by
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  • Moderator
    David Kang (Case Western Reserve University)
  • Speaker

    Oligodendrocytes, a major contributor to aging and Parkinson's disease: single-nuclei multiomic approach of human midbrain   
    Yoon-seong Kim (Rutgers, The State University of New Jersey)

    Targeting the resolution of neuroinflammatory signaling in synucleinopathies   
    Jae-Kyung Jamise Lee (University of Georgia)

    Coniferaldehyde confers neuroprotection by restoring PKM2 and inhibiting JAK2/STAT3 in a 3-NP-induced Huntington’s disease mouse mode   
    Ayooluwa Gabriel Ibiayo (Tzu Chi University)

    Mitophagy and mitochondrial proteostasis: role of CHCHD10 in ALS and FTD   
    David Kang (Case Western Reserve University)

    CHCHD2 dysfunction links the mitochondria-lysosome axis to proteinopathy and brain aging.   
    Alexa Woo (Case Western Reserve University)

  • August 25 (Mon)
    10:35-12:30
    Symposium 16. Recent advances in functional observation of ion channels and synaptic transmission
    Rm.116-118
  • Recent advances in the functional observation of ion channels and synaptic transmission have significantly enhanced our understanding of cellular communication and neural activity. Ion channels are crucial for regulating ion flow across cell membranes, essential for generating action potentials and neurotransmitter release. Techniques like high-resolution imaging, electrophysiology, and optogenetics enable real-time visualization and manipulation of these processes. These developments have opened new research avenues, providing insights into brain function mechanisms and potential therapeutic strategies for related diseases. This symposium will explore the intricate interactions between various ion channels and their impact on synaptic transmission.
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  • Organizer
    Byung-Chang Suh (Daegu Gyeongbuk Institute of Science and Technology)
  • Moderator
    Byung-Chang Suh (Daegu Gyeongbuk Institute of Science and Technology)
    Yasushi Okamura (Osaka University)
  • Speaker

    In vivo and in vitro studies on turnover of voltage-gated ion channels at the axon initial segments of mammalian neurons   
    Yasushi Okamura (Osaka University)

    Unique short-term synaptic plasticity between human cortical pyramidal neurons compared to other mammalian species such as mouse and non-human primate   
    Mean-Hwan Kim (Daegu Gyeongbuk Institute of Science and Technology)

    Towards understanding GABAergic synaptic signaling   
    Ji Won Um (Daegu Gyeongbuk Institute of Science and Technology)

    The ion channels modulating the reward circuit in the nucleus accumbens   
    Se-Young Choi (Seoul National University)

  • August 25 (Mon)
    10:35-12:30
    Symposium 17. Transforming brain networks - neuromodulation strategies for neuropsychiatric disorders
    Rm.204-205
  • This symposium aims to foster collaboration between basic scientists and clinical researchers by examining how network dynamics in epilepsy can inform neuromodulation therapies. Through a multidisciplinary approach, the symposium can be helpful to seek bridging mechanistic insights with clinical applications, paving the way for innovative therapeutic strategies for neuropsychiatric disorders, with a particular focus on epilepsy.
  • Organizer
    Hyang Woon Lee (Ewha Womans University)
    Hao-Li Liu (National Taiwan University)
  • Moderator
    Hao-Li Liu (National Taiwan University)
  • Speaker

    From bench to bedside - advancing neuromodulation therapy for intractable epilepsy   
    Hyang Woon Lee (Ewha Womans University)

    Bidirectional neuronal control of epileptiform activities by repetitive transcranial focused ultrasound   
    Jinhyoung Park (Sungkyunkwan University)

    Personalized virtual brain modeling to optimize brain stimulation towards clinical applications   
    Sora An (Ewha Womans University)

    Neuromodulatory focused ultrasound for epilepsy: cutting-edge advances and future directions   
    Hao-Li Liu (National Taiwan University)

    Human nerve tissue engineering approach for developing aging model: a novel tool for high-throughput screening of anti-aging molecules   
    Varsha Pai V (Manipal Centre for Biotherapeutics Research)

  • August 25 (Mon)
    14:30-16:25
    Symposium 18. The brain-body-microbiome axis: a key to regulate ingestion and beyond
    Grand Ballroom
  • The Brain-Body-Microbiome Axis represents an interconnected system that governs not only food ingestion but also energy homeostasis, immunity, and behavior. This axis underscores the bidirectional communication between the brain, peripheral organs (like the gut), and the microbiome. By integrating neural, hormonal, and microbial signals, this axis offers a central mechanism for regulating interoceptive sensing, feeding and various physiological processes. This symposium will explore recent advances in our understanding of the Brain-Body-Microbiome axis in regulating ingestive behavior that highlight the use of cutting-edge technologies to reveal novel mechanisms. Our goal is to encourage the sharing of unpublished data, promote lively discussions and foster new collaborations across the fields.
  • Organizer
    Greg Seong-Bae Suh (Korea Advanced Institute of Science and Technology)
  • Moderator
    Greg Seong-Bae Suh (Korea Advanced Institute of Science and Technology)
  • Speaker

    Why do we self-medicate? Knowledge gained from animals in nature.   
    Michael A. Huffman (Kyoto University)

    Circuit topology and the hierarchy of needs   
    Jing W. Wang (University of California, San Diego)

    Dissecting the mechanisms underlying gut-brain interactions in neurological disorders   
    Mauro Costa-Mattioli (Altos Labs)

    Complex interplay of hormonal, neuronal responses by gut-brain axis to a deficit in essential amino acids   
    Boram Kim (Korea Advanced Institute of Science and Technology)

    Chronic exposure to air pollutants impaired memory performance via elevating gut microbial metabolites in a mouse model   
    Akhlaq Hussain (The Hong Kong Polytechnic University)

  • August 25 (Mon)
    14:30-16:25
    Symposium 19. Taste sensing from the tongue to the brain
    Premier Ballroom A
  • This symposium will explore the biological underpinnings of taste sensing from the tongue to the brain, highlighting how different organisms perceive and respond to taste stimuli. Talks will cover topics such as the neural and sensory pathways involved in detecting bitter taste in the throat, the role of taste signals in guiding feeding behavior, and the development of innovative taste bud organoids for studying gustatory function. By bridging research across diverse model systems, this symposium aims to provide a comprehensive understanding of how taste signals influence feeding behavior.
  • Organizer
    Myunghwan Choi (Seoul National University)
    Yong Taek Jeong (Korea University)
  • Moderator
    Yong Taek Jeong (Korea University)
  • Speaker

    Channel Synapse Mediates Neurotransmission of Upper Airway Protective Chemoreflexes   
    Akiyuki Taruno (Kyoto Prefectial University)

    Understanding and targeting the taste system of dangerous mosquitoes   
    Lisa S. Baik (Yale University)

    Generation of mouse taste bud organoid and its single cell transcriptomic atlas   
    Yong Taek Jeong (Korea University)

    Taste bud connectome: patterns of connectivity in a dynamic sensory organ   
    Courtney Wilson (University of Colarado)

    Cellular basis of non-sweet aftertaste in artificial sweeteners   
    Geehyun Kim (Seoul National University)

  • August 25 (Mon)
    14:30-16:25
    Symposium 20. Updates on autism models and potential rescue strategies
    Premier Ballroom B
  • This is a "must attend" symposium for anyone -the public, members of academia and healthcare and industry alike – interested in Autism Spectrum Disorders (ASD). ASD is characterized by restricted and repetitive behaviors and deficit in social interaction with diagnosis rate of 2.8% of the children. Because ASD imposes heavy burden on the patients, their caregivers and their surroundings, a new, working therapeutic solution is called for. Unfortunately, there are no definitive treatment options, nor any means of prevention for ASD to date. In this session world-renowned speakers will introduce the latest ASD models and updates on our current understanding of ASD, and provide innovative and viable therapeutic strategies for ASD.
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  • Organizer
    Xiang Yu (Peking University)
    Mihyun Bae (Institute for Basic Science)
  • Co-organizer
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  • Moderator
    Xiang Yu (Peking University)
    Mihyun Bae (Institute for Basic Science)
  • Speaker

    Behavioral Improvement Through In Vivo Base Editing in a Mouse Model of Snijders Blok-Campeau Syndrome   
    Zilong Qiu (Shanghai Jiao Tong University)

    From mouse to cell models of autism   
    Toru Takumi (Kobe University)

    New therapeutic methods for ASD   
    Mihyun Bae (Institute for Basic Science)

    Using oxytocin to treat autism: insights from animal models   
    Xiang Yu (Peking University)

  • August 25 (Mon)
    14:30-16:25
    Symposium 21. Innovations in imaging- and sequencing-based approaches in neurosciences
    Rm.113-115
  • This symposium highlights recent breakthroughs in imaging and sequencing-based analysis methods in neuroscience. The featured research spans innovative approaches including in vivo two-photon imaging for sensory neurobiology, human whole-brain mapping, single-cell RNA sequencing techniques, advanced optical imaging for deep brain visualization, and novel tools for gene delivery and spatial transcriptomics. Together, these advances are transforming our ability to study the nervous system from molecular to system-wide scales.
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  • Organizer
    Chang Ho Sohn (Korea Advanced Institute of Science and Technology)
  • Moderator
    Chang Ho Sohn (Korea Advanced Institute of Science and Technology)
  • Speaker

    Multiscale molecular imaging and phenotyping of the human brain based on polymer hydrogel   
    Juhyuk Park (Seoul National University)

    Fixative eXchange (FX)-seq: scalable single-nucleus RNA sequencing analysis of PFA-fixed or FFPE tissue   
    Chang Ho Sohn (Korea Advanced Institute of Science and Technology)

    Deep optical imaging within complex scattering media   
    Wonsik Choi (Korea University)

    Engineering interventional neuro-omics: where viral vectors meet 3D spatial biology   
    Min Jee Jang (University of Illinois)

    Presynaptic mitochondrial capture mechanism during synapse formation   
    Kazuki Tsujimura (The University of Tokyo)

  • August 25 (Mon)
    14:30-16:25
    Symposium 22. [KSBNS-AKN Symposium] Hurting inside and out: sensing pain and nausea
    Rm.204-205
  • Understanding how the body senses and responds to external and internal discomfort signals, such as pain and nausea, is essential for addressing debilitating conditions that impact millions worldwide. This symposium will delve into cutting-edge research on the cellular, molecular, and circuit mechanisms that underlie these sensations. We will discuss the molecules, cell types, and neural circuits—both peripheral and central—that mediate the detection and transmission of somatic and visceral sensory signals that cause pain and nausea. This session will also highlight technical and conceptual advancements that tackle fundamental questions in the field and provide novel therapeutic approaches for treating pain and nausea.
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  • Organizer
    Seungwon (Sebastian) Choi (University of Texas Southwestern Medical Center)
    Hojoon Lee (Northwestern University)
  • Moderator
    Hojoon Lee (Northwestern University)
  • Speaker

    Neural basis of motion sickness   
    Hojoon Lee (Northwestern University)

    Molecular dissection of area postrema and its role in nausea   
    Chuchu Zhang (University of California, Los Angeles)

    Analysis of spinal output circuits in chronic pain   
    Seungwon (Sebastian) Choi (University of Texas Southwestern Medical Center)

    Feeling the force: PIEZO ion channels in interoception   
    Kara Marshall (Baylor College of Medicine)

  • August 25 (Mon)
    14:30-16:25
    Symposium 23. Neuromodulation in the brain: new understanding and emerging methods
    Rm.206-207
  • Diffuse modulatory systems are essential for maintaining the brain's adaptability, emotional stability, and responsiveness to internal and external cues by modulating the excitability and synaptic transmission of target neurons. Despite significant progress, the structural organization and functional features of these systems at the synaptic, neuronal, neural circuit, and behavioral levels remains largely underexplored. However, recent technological advancements and emerging discoveries are offering novel insights into the extensive influence of neuromodulatory systems, underscoring their critical role in regulating neural functions. This symposium will address key topics in current neuromodulatory system research, including: the development of new optical tools to elucidate how neuronal networks generate complex behaviors, the identification of novel biological features and functions of dopaminergic and serotonergic synapses, the role of basolateral amygdala dopamine signaling in initiating rapid eye movement sleep, and the modulation of neural ensembles by serotonin to shape trial-specific behavioral strategies.
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  • Organizer
    Jung Ho Hyun (Daegu Gyeongbuk Institute of Science and Technology)
    Jae-Ick Kim (Ulsan National Institute of Science of Technology)
  • Moderator
    Jung Ho Hyun (Daegu Gyeongbuk Institute of Science and Technology)
  • Speaker

    Illuminating the brain: new tools to unravel how neuronal networks generate complex behaviors   
    Olivia Andrea Masseck (University of Cologne)

    Modulatory synapses in the brain: new biological features and functions of dopaminergic and serotonergic synapses   
    Jae-Ick Kim (Ulsan National Institute of Science of Technology)

    Rapid eye movement sleep is initiated by basolateral amygdala dopamine signaling in mice   
    Emi Hasegawa (Kyoto University)

    Trial-resolution neural representations of behavioral strategies during reversal learning   
    Jung Ho Hyun (Daegu Gyeongbuk Institute of Science and Technology)

  • August 26 (Tue)
    08:30-10:25
    Symposium 24. [KSBNS-AKN Symposium] Convergent mechanisms for axon regeneration and CNS repair
    Premier Ballroom A
  • This session focuses on groundbreaking advancements in understanding and promoting peripheral and central nervous system regeneration and functional recovery after injury, appealing to a diverse audience within neuroscience, medicine, and therapeutic development. The session highlights innovative molecular, cellular, and systems-level strategies to repair neural damage, emphasizing the latest discoveries in axonal regeneration, immune system modulation, and functional rewiring. Speakers explore the intricate processes that underlie neural repair, such as the role of microtubule dynamics in structural remodeling, the influence of long non-coding RNAs, and the interactions between the nervous system and the immune response in plasticity and recovery.
  • Organizer
    Kevin (Kyung) Park (University of Texas Southwestern Medical Center)
    Byung Gon Kim (Ajou University)
  • Supported by
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  • Moderator
    Kevin (Kyung) Park (University of Texas Southwestern Medical Center)
    Byung Gon Kim (Ajou University)
  • Speaker

    Axon regeneration and functional rewiring after adult central nervous system injury   
    Kai Liu (Hong Kong University of Science and Technology)

    Targeting microtubule dynamics to promote axon regeneration   
    Eun Mi Hur (Seoul National University)

    Path toward vision restoration through promoting optic nerve regeneration and reconnection   
    Kevin K. Park (University of Texas Southwestern Medical Center)

    Immune modulation of CNS fibrosis   
    Jae K. Lee (University of Miami)

    Neuro-immune interaction in post-stroke plasticity and functional recovery   
    Byung Gon Kim (Ajou University)

  • August 26 (Tue)
    08:30-10:25
    Symposium 25. Decoding neuro-glial interactions: the critical role of ion channels from molecules to behaviors
    Premier Ballroom B
  • The symposium, "Decoding Neuro-Glial Interactions: The Critical Role of Ion Channels from Molecules to Behaviors," will highlight recent advancements in our understanding of Bestrophin anion channels expressed in astrocytes and retinal pigmented epithelial cells. Originally identified in Best vitelliform macular dystrophy, these channels are now recognized as key mediators of both calcium- and neurotransmitter-activated Cl⁻ transport, as well as gliotransmission. The symposium will cover structural insights from cryo-EM studies, functional mechanisms revealed by electrophysiological and mutational analyses, and the physiological roles that these channels play in retinal health, neuro-glial signaling, and animal behavior. By bringing together experts from diverse disciplines, this symposium bridges the gaps between structure-function relationships and physiological outcomes, thereby driving innovation in our understanding of ion channel-related mechanisms in both healthy and diseased states of neuro-glial interactions.
  • Organizer
    Hyun-Ho Lim (Korea Brain Research Institute)
  • Supported by
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  • Moderator
    C. Justin Lee (Institute for Basic Science)
  • Speaker

    Bestrophins: structure, function and diseases   
    Tingting Yang (Columbia University)

    Molecular insight into the structural and functional modulation of bestrophin1 channel   
    Hyun-Ho Lim (Korea Brain Research Institute)

    Bestrophin-1 mediated tonic GABA release from reactive astrocytes in kainate-injected hippocampus   
    Jin Bong Park (Seoul National University)

    Bestrophin channels regulate food swallowing in C. elegans   
    Kyuhyung Kim (Daegu Gyeongbuk Institute of Science and Technology)

  • August 26 (Tue)
    08:30-10:25
    Symposium 26. Neuroscience-inspired AI: computational insights into biological and artificial intelligence
    Premier Ballroom C
  • This symposium will explore converging ideas in neuroscience and AI research. Recent advancements in neural network-based AI models have created opportunities to uncover shared principles and strategies between these domains. This line of research promises several impacts: better understanding the brain's information processing by using the operating principles of AI models, enhancing AI design with insights from brain research, etc. Notably, modern AI systems are already becoming vital tools for analyzing neuroscience data. With our speakers, from pioneers to young researchers actively working on a range of topics mentioned above, we aim to provide participants with a comprehensive overview of current developments and to foster interdisciplinary dialogue and collaboration.
  • Organizer
    Sungho Hong (Institute for Basic Science)
    Jea Kwon (Max Planck Institute)
  • Moderator
    Sungho Hong (Institute for Basic Science)
  • Speaker

    How can we create and utilize Digital Brains?   
    Kenji Doya (Okinawa Institute of Science and Technology)

    Training neural networks using random noise   
    Se-Bum Paik (Korea Advanced Institute of Science and Technology)

    Advancing spiking neural networks for sequential modeling   
    Dongqi Han (Microsoft Research Asia)

    Transformer as a hippocampal memory consolidation model based on NMDAR-inspired nonlinearity   
    Jea Kwon (Max Planck Institute)

    An unsupervised platform with temporal link embedding that maps animal behavior   
    Sunpil Kim (Institute for Basic Science)

  • August 26 (Tue)
    08:30-10:25
    Symposium 27. Decoding Inhibition: the interplay of GABA, chloride, and astrocytes in neural function in health and disease
    Rm.113-115
  • This symposium focuses on the emerging and underexplored contributions of glial cells—particularly astrocytes—to inhibitory signaling. While the canonical view of inhibition has centered on GABAergic neurons and their ligand-gated chloride channels, recent findings indicate that astrocytes are active participants in shaping inhibitory tone. The speakers in this session will present cutting-edge research illuminating astrocytic roles in regulating extracellular GABA and chloride, thus influencing neural network function during development and aging, as well as under both physiological and pathological conditions. The speaker will provide a comprehensive overview of the multifaceted ways astrocytes control inhibition, offering new perspectives on glial contributions to inhibition.
  • Organizer
    Verena Untiet (University of Copenhagen)
    Heejung Chun (Yonsei University)
  • Moderator
    Verena Untiet (University of Copenhagen)
    Heejung Chun (Yonsei University)
  • Speaker

    Physiological role of astrocytic GABA in cerebellum   
    Bo-Eun Yoon (Dankook University)

    Astrocytes control neuronal activity by modulating extracellular ion concentrations   
    Verena Untiet (University of Copenhagen)

    Reactive astrocytes drive tau pathology via autophagy dysfunction and MAO-B upregulation in Alzheimer’s disease   
    Heejung Chun (Yonsei University)

  • August 26 (Tue)
    08:30-10:25
    Symposium 28. Epilepsy: from gene to circuit
    Rm.204-205
  • This session brings together clinicians, translational researchers, and basic neuroscience researchers to foster interdisciplinary discussions. A significant number of pediatric epilepsy patients have undergone genetic screening, providing valuable insights into the genetic underpinnings of the disorder.
    The session aims to address current clinical challenges, review recent advancements in translational research, and explore how basic neuroscience findings can be integrated into clinical practice to improve diagnostic and therapeutic strategies for pediatric epilepsy.
  • Organizer
    Won Seok Chang (Yonsei University)
    Eunee Lee (Yonsei University)
  • Co-Organizer
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  • Moderator
    Won Seok Chang (Yonsei University)
  • Speaker

    Understanding neurodevelopmental and seizure patterns in monogenic epilepsies   
    Se Hee Kim (Yonsei University)

    The intersection between autism and epilepsy in SCN2A-related neurodevelopmental disorders   
    Kevin Bender (University of California, San Francisco)

    Neurosurgical approach for intractable epilepsy from bench to clinic   
    Won Seok Chang (Yonsei University)

    Electrophysiological hallmarks of epilepsy and autism in the human neocortex   
    Jaeyoung Yoon (Harvard University)

  • August 26 (Tue)
    08:30-10:25
    Symposium 29. Decoding the neurobiology of acupuncture through modern neuroscientific approaches
    Rm.206-207
  • Despite millennia of clinical practice, the neurobiological mechanisms underlying the therapeutic effects of acupuncture in pathological conditions such as systemic inflammation, pain, neurodegenerative diseases, and mental disorders remain elusive. Recent advances in neuroscience have begun to uncover these mechanisms, revealing how acupuncture exerts its effects from the periphery to the brain across multiple levels, including molecular, cellular, and circuit dynamics. This symposium will highlight groundbreaking findings on the neurobiological basis of acupuncture, including novel mechanisms of its anti-inflammatory effects mediated via the vagal-adrenal axis, its anti-parkinsonian effects involving hypothalamic circuits and the gut-brain axis, and its anti-depressant effects through astrocyte modulation. These studies represent a cornerstone for decoding acupuncture's therapeutic actions and provide a strong foundation for future translational research.
  • Organizer
    Min-Ho Nam (Korea Institute of Science and Technology)
    Hi-Joon Park (Kyung Hee University)
  • Moderator
    Min-Ho Nam (Korea Institute of Science and Technology)
    Hi-Joon Park (Kyung Hee University)
  • Speaker

    Neuroanatomical organization of electroacupuncture in modulating gastric function in mice and humans   
    Shenbin Liu (Fudan University)

    Central role of hypothalamic circuits for acupuncture’s anti-parkinsonian effects   
    Min-Ho Nam (Korea Institute of Science and Technology)

    Decoding the hypothalamic-gut axis: Acupuncture's role in microbial and gastrointestinal homeostasis through neural circuit modulation   
    Hi-Joon Park (Kyung Hee University)

    Vascular endothelial cell-secreted protein acts as a bridge for early periphery-to-brain inflammatory signaling   
    Qiuzi Wu (Peking University)

  • August 26 (Tue)
    10:35-12:30
    Symposium 30. Precise dissection of structural and functional features in visual system
    Premier Ballroom B
  • The visual system, responsible for our sense of sight, is a complex and intricate network of structures and functions. Precise dissection of this system involves a meticulous examination of its components, from the eye itself to the neural pathways that connect it to the brain. In this symposium, speakers will present recent progress in the analysis of functional features such as phototransduction, neural signal transmission, and image processing. Advanced techniques like neuroimaging, patch-seq and electrophysiology play a crucial role in this dissection, allowing researchers to map neural activity and visualize the dynamic processes underlying vision.
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  • Organizer
    Jiayi Zhang (Fudan University)
    Hailan Hu (Zhejiang University)
  • Moderator
    Wei Li (National Institutes of Health)
    Jiayi Zhang (Fudan University)
  • Speaker

    Functionally distinct GABAergic amacrine cell types regulate spatiotemporal encoding in the mouse retina   
    Keisuke Yonehara (National Institute of Genetics)

    Single-cell transcriptomics and electrophysiology in primate visual system   
    Sheng Liu (Sun Yat-sen University)

    Altered visuomotor responses in achiasmatic Vax1AA/AA mice   
    Jin Woo Kim (Korea Advanced Institute of Science and Technology)

    How robust is the retina? Visual responses in a severely disorganized circuit   
    Chieko Koike (Ritsumeikan University)

    An integrative decoding of the visual-auditory bimodal system: circuit mapping, computational modeling, and neurotechnology innovation   
    Kexin Yuan (Tsinghua University)

  • August 26 (Tue)
    10:35-12:30
    Symposium 31. Frontiers in addiction: linking neural mechanisms to public health strategies
    Premier Ballroom C
  • This symposium explores the intersection of neurobiology and policy in addressing drug addiction, bringing together leading experts from NIDA and cutting-edge circuit researchers. It highlights recent advances in understanding addiction's neural mechanisms, including reward circuitry and synaptic plasticity, while discussing their implications for evidence-based policy and treatment strategies. Novel approaches, such as precision medicine, neurotechnologies, and cross-species translational studies, will be showcased. By integrating basic science with societal impact, the session aims to engage researchers, clinicians, and policymakers in a dialogue that bridges laboratory discoveries and real-world applications.
  • Organizer
    Ja Wook Koo (Korea Brain Research Institute)
    Heh-In Im (Korea Institute of Science and Technology)
  • Supported by
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  • Moderator
    Ja Wook Koo (Korea Brain Research Institute)
  • Speaker

    Innovative approaches for treating drug overdose: insights from preclinical and community research   
    Sandra Comer (Columbia University)

    Rewiring of prelimbic inputs to the nucleus accumbens core underlies cocaine-induced behavioral sensitization   
    Suk-Ho Lee (Seoul National University)

    Neural circuit and social mechanism of drug addiction   
    Yingjie Zhu (Chinese Academy of Sciences)

    Protracted neurobehavioral and microRNA deficits by acute nicotine dependence in mice   
    Heh-In Im (Korea Institute of Science and Technology)

    Therapy or threat? Behavioural insights into kratom’s dual role in addiction from a zebrafish study   
    Nur Sabrina Abdul Basit (Monash University Malaysia)

  • August 26 (Tue)
    10:35-12:30
    Symposium 32. Connecting the Dots: illuminating the brain from connectivity to function
    Rm.113-115
  • Understanding the brain requires bridging the gap between connectivity, cellular composition, activity, and function. Recent breakthroughs in imaging technologies—super-resolution microscopy, large-scale connectomics, and advanced optical imaging—have revolutionized our ability to visualize neural circuits and sensory systems in action. This symposium will highlight pioneering approaches, including the reconstruction of brain-wide connectivity, dynamic imaging of synaptic and neurovascular interactions, and manipulation of neural circuits to link activity with behavior. Featuring leading experts, this session will explore how these innovative methods are transforming our understanding of brain function and inspiring new avenues for research across the neural and sensory sciences.
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  • Organizer
    Jinhyun Kim (Korea Institute of Science and Technology)
    Jong-Hyun Park (Korea Institute of Science and Technology)
  • Supported by
    Highlight Image
  • Moderator
    Jinhyun Kim (Korea Institute of Science and Technology)
    Jong-Hyun Park (Korea Institute of Science and Technology)
  • Speaker

    Energetics and competitive neural and vascular interactions shape blood-flow dynamics in cortex   
    David Kleinfeld (University of California, San Diego)

    Super-resolution shadow imaging of brain tissue in vivo   
    Valentin Nägerl (Goettingen University)

    Visualizing brain-wide connectivity with fluorescence micro-optical sectioning tomography   
    Qingming Luo (Hainan University)

    Live imaging of neuroglia-like interaction in the taste bud   
    Myunghwan Choi (Seoul National University)

    Imaging neuronal activity in the cerebellar cortex of behaving mice   
    Bernd Kuhn (Okinawa Institute of Science and Technology)

  • August 26 (Tue)
    10:35-12:30
    Symposium 33. [KSBNS-KNPA Joint Symposium] Neuroscience of schizophrenia: from structure to function
    Rm.116-118
  • Schizophrenia is a significant psychiatric disorder characterized by substantial functional decline and a chronic trajectory, accompanied by psychotic symptoms like auditory hallucinations and delusions. Schizophrenia is considered as a brain disorder associated with structural and functional abnormalities. Consequently, expanding our understanding of these abnormalities is crucial for comprehending the pathophysiology of schizophrenia and improving patient treatments. In this symposium, speakers will discuss the latest research findings on the structural and functional aspects of the brains of schizophrenia patients.
  • Organizer
    Minah Kim (Seoul National University)
  • Moderator
    Jun Soo Kwon (Hanyang University)
  • Speaker

    Structural abnormalities of the brain and its clinical implications in schizophrenia   
    Sung Woo Joo (Asan Medical Center)

    Reactive astrocyte dysfunction in schizophrenia   
    Minah Kim (Seoul National University)

    Surface-based techniques for brain shape analysis in schizophrenia   
    Ilwoo Lyu (Pohang University of Science and Technology)

    Electrophysiological studies of schizophrenia using mismatch negativity   
    Daisuke Koshiyama (The University of Tokyo)

    Exploring the interplay between macrostructural and microstructural brain abnormalities in psychosis   
    Sun-Young Moon (Seoul National University)

  • August 26 (Tue)
    10:35-12:30
    Symposium 34. Local mRNA translation in axon development, health and function
    Rm.206-207
  • RNA-based mechanisms play important roles in axonal development, maintenance, and regeneration, regulating processes of protein synthesis, localization, and structural integrity. This symposium will explore new research on RNA regulation in axons, including local translation, RNA transport, and non-coding RNA functions. Highlighting innovative techniques like high-resolution imaging and RNA sequencing, the talks will uncover novel insights into RNA-protein interactions and their therapeutic potential. With a focus on bridging fundamental neuroscience and translational research, this session aims to captivate a broad audience by revealing the dynamic interplay between RNA biology and axonal function, addressing key challenges in understanding and treating neurological disorders.
  • Organizer
    Yongcheol Cho (Daegu Gyeongbuk Institute of Science and Technology)
  • Moderator
    Yongcheol Cho (Daegu Gyeongbuk Institute of Science and Technology)
  • Speaker

    Local mRNA translation in axons sustains synapse-specific neurotransmission   
    Hovy H. Wong (The Chinese University of Hong Kong)

    Preserved synaptic function after axon injury is mediated by mTOR-driven local translation and reveals novel disease-linked candidates   
    Marco Terenzio (Okinawa Institute of Science and Technology)

    Regulation of axonal translation via control of ribosomal protein mRNA localization in regenerating axons   
    Jung Eun Shin (Dong-A University)

    Exploring the functional diversity of epitranscriptomic modifications in gene regulation and disease   
    Ki-Jun Yoon (Korea Advanced Institute of Science and Technology)

  • August 26 (Tue)
    14:30-16:25
    Symposium 35. Synaptic development, function, and brain disorders
    Grand Ballroom
  • This session explores cutting-edge insights into synaptic function, development, and their roles in neuropsychiatric disorders. Morgan Sheng presents molecular mechanisms linking genetic mutations to schizophrenia. Peter Scheiffele highlights selective mRNA translation's impact on neuronal plasticity and disorders, including autism. Matthijs Verhage discusses synaptic gene mutations underlying neurodevelopmental disorders and intervention strategies. Yelin Chen delves into synaptic mechanisms driving brain development and Alzheimer's disease. Heera Moon, a postdoctoral fellow, will discuss synaptic and neuronal mechanisms underlying sensory abnormalities in mouse models of autism. Together, these talks provide a comprehensive view of synaptic development and function in health and brain disorders for potential therapeutic avenues.
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  • Organizer
    Eunjoon Kim (Korea Advanced Institute of Science and Technology / Institute for Basic Science)
  • Co-organizer
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  • Moderator
    Eunjoon Kim (Korea Advanced Institute of Science and Technology / Institute for Basic Science)
  • Speaker

    From human genetics to animal models to potential novel therapeutics for schizophrenia   
    Morgan Sheng (Massachusetts Institute of Technology)

    Control of neurodevelopmental gene expression programs and circuit assembly by spontaneous neuronal activity in the mouse visual cortex   
    Peter Scheiffele (University of Basel)

    Disease mechanisms and intervention strategies for neurodevelopment disorders caused by mutations in presynaptic genes   
    Matthijs Verhage (Vrije University)

    Synaptic mechanisms for brain development and antidepressant responses   
    Yelin Chen (Shanghai Institute of Organic Chemistry)

    Cortical mechanisms underlying sensory hypersensitivity in Adnp-mutant mice   
    Heera Moon (Korea Advanced Institute of Science and Technology)

    Perturbed cell fate decision by schizophrenia-associated AS3MTd2d3 isoform during corticogenesis   
    Seunghyun Kim (Pohang University of Science and Technology)

  • August 26 (Tue)
    14:30-16:25
    Symposium 36. Computational neuroethology of social and cognitive behaviors
    Premier Ballroom A
  • The symposium explores the neural mechanisms underlying complex social interactions and cognitive functions. Traditional neuroscience has made significant strides in understanding the sensorimotor, social and cognitive behaviors of diverse animal systems. However, behaviors observed in artificial experimental setups are often constrained and unnatural. To address this, computational neuroethology has emerged as a framework that minimizes these constraints and adopts quantitative, machine-learning-based approaches to uncover behavioral principles. This paradigm has provided valuable insights into the multi-timescale and hierarchical nature of behavior, collective behaviors in naturalistic environments, critical factors of major disease like epilepsy, and even evolutionary traits of species. In this symposium, we bring together speakers leveraging computational neuroethology to uncover fundamental behavioral principles and discuss how these naturalistic behaviors can be integrated with neural activity to link behavior and brain function.
  • Organizer
    Jeongjin Kim (Korea Institute of Science and Technology)
    Ain Chung (Korea Advanced Institute of Science and Technology)
  • Moderator
    Jeongjin Kim (Korea Institute of Science and Technology)
    Ain Chung (Korea Advanced Institute of Science and Technology)
  • Speaker

    Ethological and neural dynamics of collective foraging behavior in mice   
    Jee Hyun Choi (Korea Institute of Science and Technology)

    Mechanistic theory of social foraging   
    Ahmed EI Hady (Max Planck Institute)

    Computational neuroethological approaches for neurological disease   
    Seng Bum Michael Yoo (Sungkyunkwan University)

    Chaotic worms: integrative insights from the dynamics of animal behavior   
    Greg Stephens (Vrije University)

    Neural substrate of visual valence in the primate amygdala   
    Gwangsu Kim (Massachusetts Institute of Technology)

  • August 26 (Tue)
    14:30-16:25
    Symposium 37. Cross-regional brain circuit development: from neural differentiation to functional brain networks
    Premier Ballroom B
  • Neuronal circuits across specific areas in the brain are primarily established during developmental periods based both on genetic and environmental factors. The developmental mechanism of neuronal circuit formation within a specific brain area has been intensively investigated. Recent studies further advance our understanding of how cross-regional circuits are formed and the development of individual regions of the brain is orchestrated to acquire cognitive functions. This symposium highlights the development of cross-regional circuits, offering a comprehensive overview of studies spanning different temporal stages—from neuronal progenitors to functional networks—and scales, ranging from single cells to whole-brain networks.
  • Organizer
    Keiko Tanaka-Yamamoto (Korea Institute of Science and Technology)
    Yoko Yazaki-Sugiyama (Okinawa Institute of Science and Technology)
  • Moderator
    Keiko Tanaka-Yamamoto (Korea Institute of Science and Technology)
    Yoko Yazaki-Sugiyama (Okinawa Institute of Science and Technology)
  • Speaker

    Mitotic bookmarking in brain development   
    Yan Song (Peking University)

    Excavating growth cone architecture from the developing neocortex with volumeEM   
    Yu Nakanishi (The University of Tokyo)

    Opposite fine disorganization of the neocortex associated with Down Syndrome and Autism Spectrum Disorder   
    Song-Hai Shi (Tsinghua University)

    Dynamics auditory to motor circuits for developmental song learning in zebra finches   
    Yoko Yazaki-Sugiyama (Okinawa Institute of Science and Technology)

    The role of salience and action mode networks during the development of an internal-external functional brain axis in humans   
    Seok-Jun Hong (Sungkyunkwan University)

  • August 26 (Tue)
    14:30-16:25
    Symposium 38. Molecular probing of cognitive processes
    Premier Ballroom C
  • This symposium brings together leading early career researchers from China, Korea and Japan to explore the molecular, cellular, and circuit-level mechanisms of cognition. The talks will illuminate how precision design of molecular probes can shed light on molecular and circuit mechanisms critical in health and disease, through a range of cellular and animal studies across biological scales.
  • Organizer
    Haruhiko Bito (The University of Tokyo)
    Xiao-Hong Xu (Fudan University)
  • Moderator
    Haruhiko Bito (The University of Tokyo)
    Xiao-Hong Xu (Fudan University)
  • Speaker

    Rational engineering of XCaMP-C, a versatile genetically-encoded Ca2+ indicator for all-optical interrogation, multiplex and quantitative Ca2+ imaging   
    Hajime Fujii (The University of Tokyo)

    Brain-wide protein profiling using 3D immunolabeling techniques   
    Young-Gyun Park (Korea Advanced Institute of Science and Technology)

    Dissection of monoamine circuits using GRAB sensors   
    Jianzhi Zeng (Shenzhen Bay Laboratory)

    An insular cortical circuit required for itch sensation and aversion   
    Xiao Min Zhang (Sun Yat-sen University)

    Molecular mechanisms mediating engram ensemble retrievability state in mice   
    Sungmo Park (The Hospital for Sick Children)

  • August 26 (Tue)
    14:30-16:25
    Symposium 39. Next-generation genetically encoded sensors and actuators for brain exploration
    Rm.113-115
  • Synthetic protein engineering has revolutionized modern neuroscience, as exemplified by the development of fluorescent proteins for visualization and optogenetic tools for manipulation of brain function. These molecular innovations have enabled direct observation and control of specific cellular events in the living brain. This symposium brings together leading experts to showcase next-generation technologies for brain research. Recent breakthroughs include genetically encoded sensors detecting calcium ions, membrane voltage, metabolites, and transmitters, as well as powerful actuators for precise neuromodulation. These innovative tools provide fundamental insights that appeal to a broad range of neuroscientists, from molecular to behavioral researchers, advancing our understanding of brain mechanisms in health and disease while inspiring new therapeutic strategies.
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  • Organizer
    Sangkyu Lee (Institute for Basic Science)
  • Moderator
    Sangkyu Lee (Institute for Basic Science)
  • Speaker

    Evolving towards the highest-performance biosensors of neuronal signalling and metabolism   
    Robert E. Campbell (The University of Tokyo)

    Voltage imaging reveals biophysical basis of associative plasticity rules   
    Pojeong Park (Daegu Gyeongbuk Institute of Science and Technology)

    Large-scale in vivo imaging of neuronal firing with a high-contrast voltage indicator   
    Sungmoo Lee (Stanford University)

    Genetically encoded sensors and actuators for neurotransmitter receptors   
    Jihye Seong (Seoul National University)

    Sculpting neural circuits via engineered neuron-astrocyte interactions   
    Sangkyu Lee (Institute for Basic Science)

  • August 26 (Tue)
    14:30-16:25
    Symposium 40. [KSBNS-KSND Joint Symposium] Basic and translational researches on myelination and demyelination
    Rm.116-118
  • The myelin sheath is the essential structure for rapid transmission of axonal action potential in central and peripheral nervous system. Oligodendrocytes and Schwann cells are glial cells those make the myelin sheath. Multiple sclerosis, Leukodystrophy and Charcot Maire tooth disease are major myelin sheath disorders in which the integrity of myelin sheath is damaged by inflammation and abnormal production of myelin proteins and lipids. In this symposium, four myelin specialists encompassing central and peripheral myelin researches will show most recent data concerning the pathophysiological mechanism of demyelinating Charcot Maire tooth disease 1A and central myelin disorders. In addition, novel molecular players of myelination and Ranvier node formation will be presented. These symposium will provide an important insight into the mechanistic aspects of myelin disease development and therapeutic potential for those diseases.
  • Organizer
    Hwan Tae Park (Dong-A University)
    Hyun-Jeong Yang (University of Brain Education)
  • Moderator
    Hwan Tae Park (Dong-A University)
  • Speaker

    The role of oligodendrocyte lineage cells in the hypothalamus   
    Dong Ho Woo (Korea Institute of Toxicology)

    Searching for novel myelination-promoting factors in the central nervous system   
    Hyun-Jeong Yang (University of Brain Education)

    Oligodendroglial precursor cells orchestrate immune crosstalk at the onset of multiple sclerosis   
    Qi Wang (Sun Yat-sen University)

    Nerve-specific gene therapy for CMT1A: safety, efficacy and biomarker characterization in sheep   
    Nicolas Tricaud (Inserm)

    Differential subcellular distribution of cell adhesion molecules in neurons guides myelin targeting   
    Elior Peles (Weizmann Institute of Science)

  • August 26 (Tue)
    14:30-16:25
    Symposium 41. Pleiotropic roles of mitochondria in neurobiology
    Rm.206-207
  • Neurons are polarized cells with a soma, dendrites, and axons, whose structural polarization drives functional specialization and organelle roles. Mitochondria, essential neuronal organelles, show distinct morphologies by location: dendritic mitochondria are elongated and tubular, while axonal ones are shorter and punctate. These forms support region-specific functions like ATP production, ROS regulation, and calcium clearance. Mitochondria adapt dynamically to physiological and pathological conditions and interact with organelles to maintain synaptic transmission and cellular homeostasis, crucial for neuronal survival. This symposium explores mitochondrial roles in neurobiology using advanced imaging to unveil mechanisms vital to neuronal integrity and function.
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  • Organizer
    Seok-Kyu Kwon (Korea Institute of Science and Technology)
  • Moderator
    Jun Young Heo (Chungnam National University)
    Seok-Kyu Kwon (Korea Institute of Science and Technology)
  • Speaker

    Hitch-hiking of mRNAs on mitochondria   
    Angelika Harbauer (Max Planck Institute)

    A mitochondrial switch of cell fate decision in early corticogenesis   
    Sang Ki Park (Pohang University of Science and Technology)

    Organellar pathogenesis in Neurodegenrative diseases   
    Kyu-Sun Lee (Korea Research Institute of Bioscience and Biotechnology)

    Correlative organelle microscopy with multimodal data to study mitochondria in lipid related neuronal developmental disorders   
    Ji Young Mun (Korea Brain Research Institute)

    In situ localization of ER-mitochondria tethering proteins at the nanometer scale   
    Takumi Sakano (The University of Tokyo)

  • August 27 (Wed)
    09:00-10:55
    Symposium 42. Unlocking pathophysiological and novel therapeutic mechanisms for mood disorders: insights from synapse research
    Grand Ballroom
  • Depression affects 1 in 6 adults globally, with traditional monoamine-targeting antidepressants often requiring weeks to take effect and failing in one-third of cases. In contrast, ketamine and psilocybin provide rapid antidepressant effects within hours or days of just one or two doses, with benefits lasting weeks to months. These breakthroughs have shifted attention to synaptic and glutamatergic systems as critical targets in depression treatment. Leading experts at this symposium will discuss the mechanisms underlying these rapid effects, including the roles of astrocytic and synaptic networks, brain circuit reorganization, and psilocybin's impact on cortical and claustral systems. Join us to explore how these innovative therapies are transforming treatment approaches and bringing hope to patients resistant to traditional methods.
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  • Organizer
    Ji-Woon Kim (Kyung Hee University)
  • Moderator
    Ji-Woon Kim (Kyung Hee University)
  • Speaker

    The role of astrocytic PLCh1 in the lateral habenula associated with depression   
    Jeongyeon Kim (Korea Brain Research Institute)

    Functional nano-organization of central synapses and rapid antidepressant action   
    Ege T. Kavalali (Vanderbilt University)

    Mechanism of rapid antidepressant action   
    Lisa M. Monteggia (Vanderbilt University)

    Neurophysiological effects of psilocybin on the cortical and claustral circuits   
    Juhyun Kim (Korea Brain Research Institute)

    Stress-induced spontaneous high-frequency firing in the hippocampus promotes synaptic diversity and memory encoding through entropy expansion   
    Yuheng Yang (Yamaguchi University)

  • August 27 (Wed)
    09:00-10:55
    Symposium 43. Astrocyte heterogeneity from neural networks to behaviors
    Premier Ballroom A
  • Once considered a type of glue cell, astrocytes are now recognized as key regulators of various brain functions. The symposium "Astrocyte Heterogeneity: From Neural Network to Behavior" delves into the multifaceted roles of astrocytes, spanning instinctive behaviors, cognitive functions, and mental health disorders. Presenting cutting-edge discoveries that link cellular mechanisms to behavioral outcomes, this symposium aims to cover the intricate functions of astrocytes within specific neural circuits. The talks in this session seek to disseminate and deliberate on the latest forefront research concerning astrocyte functions, highlighting the heterogeneity present within distinct neural networks. Its broad appeal stems from the fusion of fundamental scientific insights with clinical relevance, providing valuable perspectives on potential therapeutic targets for neurological and psychiatric disorders.
  • Organizer
    Ruotian Jiang (Sichuan University)
    Wuhyun Koh (Institute for Basic Science)
  • Co-organizer
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  • Moderator
    Ruotian Jiang (Sichuan University)
    Kyungchul Noh (Ajou University)
  • Speaker

    A novel form of region-specific astrocyte morphological plasticity involved in instinct behaviors   
    Ruotian Jiang (Sichuan University)

    Divergent roles of prefrontal astrocytes in social dominance behavior and victory   
    Kyungchul Noh (Ajou University)

    Prefrontal cortex astrocytes modulate distinct neuronal populations to control anxiety-like behavior   
    Xinzhu Yu (University of Illinois)

    An astroglial basis of major depressive disorder: molecular, cellular, and circuit heterogeneity   
    Xiong Cao (Southern Medical University)

    Astrocytic phagocytosis during sleep controls systems consolidation   
    Won-Suk Chung (Korea Advanced Institute of Science and Technology)

  • August 27 (Wed)
    09:00-10:55
    Symposium 44. Audiovisual processing in rodents and marmosets
    Premier Ballroom B
  • Mammals make optimal decisions based on sensory information through brain-wide sensory processing and decision-making. This symposium explores recent findings on audiovisual processing in the mammalian brain. Three speakers will discuss how visual feature selectivity emerges in the visual cortex, from the striate to the extrastriate cortex, using mouse and marmoset models. Two speakers will focus on neural circuit mechanisms of auditory perceptual decision-making, highlighting its flexibility in complex environments, primarily using a mouse model. Together, this symposium provides insights into how the mammalian brain processes audiovisual information and supports decision-making in dynamic sensory contexts.
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  • Organizer
    Seung-Hee Lee (Korea Advanced Institute of Science and Technology/Institute for Basic Science)
    Soo Hyun Park (Korea Advanced Institute of Science and Technology)
  • Co-organizer
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  • Moderator
    Seung-Hee Lee (Korea Advanced Institute of Science and Technology/Institute for Basic Science)
    Soo Hyun Park (Korea Advanced Institute of Science and Technology)
  • Speaker

    Orthogonalization of spontaneous and stimulus-driven activity by hierarchical neocortical areal network in primates   
    Kenichi Ohki (The University of Tokyo)

    Synaptic molecules tune neuronal feature selectivity: novel in vivo imaging techniques and gene therapy development   
    Ingie Hong (Johns Hopkins University)

    Dynamic visual processing in marmoset extrastriate cortex   
    Soo Hyun Park (Korea Advanced Institute of Science and Technology)

    Dendritic and circuit computation for flexible decision-making   
    Ning-long Xu (Chinese Academy of Sciences)

    Balancing flexibility and stability during auditory reversal learning   
    Seung-Hee Lee (Korea Advanced Institute of Science and Technology/Institute for Basic Science)

  • August 27 (Wed)
    09:00-10:55
    Symposium 45. Brain cell atlas and technology
    Premier Ballroom C
  • The "Brain Cell Atlas and Technology" symposium highlights cutting-edge advances in mapping the brain at cellular and molecular resolutions. Talks will showcase breakthroughs in 3D brain atlases, including the mouse lemur and human protein atlas, and innovations in cerebral cortex connectomics. The speakers will also explore integrative studies linking connectomes to functional insights in sensory systems, as well as single-cell spatial transcriptomics and whole-brain connectivity of the macaque claustrum. This symposium offers novel perspectives and tools, appealing to researchers in neuroscience, systems biology, and translational medicine, aiming to deepen our understanding of brain organization and function.
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  • Organizer
    Shiping Liu (BGI-Research)
    Ying Lei (BGI-Research)
  • Moderator
    Linqing Feng (Zhejiang Lab)
  • Speaker

    eLemur: A cellular-resolution 3D atlas of the mouse lemur brain   
    Jinhyun Kim (Korea Institute of Science and Technology)

    The human protein atlas (HPA) a neuroscience resource   
    Jan Mulder (Karolinska Institute)

    Cerebral cortex connectomics   
    Moritz Helmstaedter (Max Planck Institute)

    From connectome to functional study for somatorsensory system   
    YanGang Sun (Chinese Academy of Sciences)

    Single-cell spatial transcriptome atlas and whole-brain connectivity of the macaque claustrum   
    Ying Lei (BGI-Research)

  • August 27 (Wed)
    09:00-10:55
    Symposium 46. [KSBNS-KNA Joint Symposium] Emerging mechanisms in white matter injury: autoimmunity, vascular dysfunction, and lipid metabolism
    Rm.116-118
  • This seminar has been organized to expand the focus on translational and clinical neuroscience, fostering collaboration between the Korean Neurological Association (KNA) with KSBNS. While covering a range of neurological disorders, it emphasizes white matter injury and its diverse mechanisms. The seminar aims to highlights integrative interactions and insights that enhance our understanding of these conditions. To achieve this, the program features two distinguished domestic speakers with extensive clinical expertise and translational research perspectives. Additionally, we are honored to include two international speakers from Stanford University, USA, and the National Neuroscience Institute, Singapore.
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  • Organizer
    Sun Ah Park (Ajou University)
  • Moderator
    Sun Ah Park (Ajou University)
  • Speaker

    Single-cell immune profiling reveals distinct CSF and blood signatures distinguishing MOGAD from MS and NMOSD in treatment-naïve patients   
    Charlotte Ng (Korea Institute of Science and Technology)

    CNS autoimmune diseases involving white matter   
    Young Nam Kwon (Yonsei University)

    Hereditary vascular dysfunctions resulting in white matter ischemic disorders   
    Jay Chol Choi (Jeju National University)

    Survival signaling pathways of oligodendrocyte lineage cells in ischemic white matter injury   
    Jun Young Choi (Ajou University)

    Dysfunction of lipid metabolism in astrocytes as emerging mechanism in Alzheimer's disease   
    Zeng Li (Duke-NUS Medical School)

  • August 27 (Wed)
    12:30-14:25
    Symposium 47. Recent insights into molecular orchestration of synaptic transmission and neural circuit modulation
    Premier Ballroom A
  • Synapses are the key driver of neural circuit activity and animal behaviors that result from it. Synaptic cellular and molecular machinery coordinates signaling from gene expression to communication with the surrounding cellular environment and impacts neuronal network functions. This symposium highlights recent findings from rodent and drosophila model systems that provide deeper views on the topic.
  • Organizer
    Yukiko Goda (Okinawa Institute of Science and Technology)
    Huan Ma (Zhejiang University)
  • Moderator
    Yukiko Goda (Okinawa Institute of Science and Technology)
    Huan Ma (Zhejiang University)
  • Speaker

    Cognitive aging and its sex-specific regulation: mechanisms and insights   
    Huan Ma (Zhejiang University)

    Cortico-hippocampal CA1 direct circuits for learning and memory   
    Xiaohui Zhang (Beijing Normal University)

    An actin-regulatory pathway governing the maintenance of presynaptic homeostatic plasticity   
    Seungbok Lee (Seoul National University)

    Presynaptic metabolism of phosphoinositides   
    Shigeo Takamori (Doshisha University)

    Unique dynamics and distinguishable subsets of spontaneously recycled inhibitory synaptic vesicles   
    Chungwon Park (The Hong Kong University of Science and Technology)

    Synapse-astrocyte interactions in fine-tuning of synaptic strengths   
    Yukiko Goda (Okinawa Institute of Science and Technology)

  • August 27 (Wed)
    12:30-14:25
    Symposium 48. The molecular, cellular and circuitry mechanism of pain and itch
    Premier Ballroom B
  • Pain and itch are essential sensations that play critical roles in protecting humans and other organisms. However, chronic pain and chronic itch represent significant global health challenges. These sensations are detected by DRG neurons and transmitted to the spinal cord, thalamus, and brain regions. In this symposium, five professors will explore the molecular, cellular, and circuitry mechanisms underlying pain and itch. Topics will include TRP channels and purinergic receptors, inflammatory mediator-driven interactions between neurons and glial cells, and promising molecular targets for pain and itch treatments. The symposium aims to highlight recent advancements and foster a deeper understanding of the mechanisms underlying these sensations.
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  • Organizer
    Yongjing Gao (Nantong University)
    Guang-Yin Xu (Soochow University)
  • Moderator
    Yongjing Gao (Nantong University)
  • Speaker

    Thermosensitive TRP channels in itch and pain   
    Makoto Tominaga (Nagoya City University)

    Mechanisms linking peripheral injury repair and neuropathic pain   
    Yun Wang (Peking University)

    Purinergic receptors and chronic pain   
    Guang-Yin Xu (Soochow University)

    Neuronal circuitry and plasticity of pain   
    Yong Ho Kim (Gachon University)

    Neuroinflammation and neuropathic pain   
    Yong-Jing Gao (Nantong University)

    FTO demethylase modulates neuropathic pain through m6A-mediated presynaptic control of Cav2.2 channels   
    Jianxiong Wei (Xi'an Jiaotong University)

  • August 27 (Wed)
    12:30-14:25
    Symposium 49. Emergence, maintenance, and entrainment of circadian clocks: from molecules to networks
    Premier Ballroom C
  • We bring together leading researchers in East Asia to trace the developmental origins and maintenance of circadian clocks, from stem cells and animals to tissue-wide emergence and network entrainment. Kazuhiro Yagita (Japan) discusses the developmental emergence of circadian oscillations in mammals using mouse ES cells and embryos. Eun Young Kim (Korea) examines molecular period determination within the Drosophila clock. Jihwan Myung (Taiwan) discusses early circadian clock emergence in a mouse brain locus outside the suprachiasmatic nucleus via programmed bifurcation. Shih-Kuo Chen (Taiwan) shares insights into circadian clock network entrainment to external light through in vivo SCN imaging. Together, a molecular and developmental picture of the circadian clock is presented.
  • Organizer
    Jihwan Myung (Taipei Medical University)
  • Moderator
    Jihwan Myung (Taipei Medical University)
  • Speaker

    Impact of the emergence of circadian clock on the developmental physiology in mammals   
    Kazuhiro Yagita (Kyoto Prefectural University)

    PPIase facilitates robust circadian rhythms via dual regulation of PERIOD protein dynamics in drosophila   
    Eun Young Kim (Ajou University)

    Early emergence of peripheral clocks through abrupt bifurcation in the mouse embryo   
    Jihwan Myung (Taipei Medical University)

    Revealing the dynamic eocoding of light in the mice SCN using in vivo calcium imaging   
    Shih-Kuo Chen (National Taiwan University)

  • August 27 (Wed)
    12:30-14:25
    Symposium 50. Decoding GPCR signaling: innovations in neuroscience research
    Rm.113-115
  • Recent advances in GPCR research have revolutionized our understanding of neuronal signaling and brain function. This symposium will highlight cutting-edge approaches decoding GPCR signaling in the nervous system, from innovative structural biology techniques revealing conformational dynamics to new optogenetic biosensors enabling precise spatiotemporal monitoring of GPCR activity. Topics will span multiple scales - from molecular and cellular mechanisms to circuit function. This symposium will appeal broadly to neuroscientists, cell biologists, and drug developers interested in GPCR biology and its translation to treating brain diseases.
  • Organizer
    Ka Young Chung (Sungkyunkwan University)
  • Sponsored by
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  • Moderator
    Jihye Seong (Seoul National University)
  • Speaker

    Molecular mechanism of β-arrestin interaction with phosphorylated GPCRs and phosphatidylinositol 4,5-bisphosphate   
    Ka Young Chung (Sungkyunkwan University)

    Structural and pharmacological analysis of serotonin receptor   
    Kuglae Kim (Yonsei University)

    Illuminating spatial organization of GPCR signaling in the living cell   
    Yonghoon Kwon (Gwangju Institute of Science and Technology)

    An expanded palette of ATP and adenosine sensors for multiplex imaging   
    Zhaofa Wu (Chinese Academy of Sciences)

    In vivo multiplex imaging of dynamic neurochemical networks with designed far-red dopamine sensors   
    Yu Zheng (Peking University)

  • August 27 (Wed)
    12:30-14:25
    Symposium 51. Cognitive and computational neuroscience in nonhuman primate
    Rm.116-118
  • The symposium, "Cutting-edge Non-human Primate Neuroscience," brings together leading experts to explore groundbreaking research on high-level cognitive processes in non-human primates. Featuring invited speakers Ning Liu, Liping Wang, Kentaro Miyamoto, and Shigeru Kitazawa, the event will highlight advancements in functional MRI and electrophysiology for studying brain mechanisms underlying high-level cognition and behavior. Sessions will delve into the neural basis of sequence working memory, high-level vision, executive functions, and decision-making. Join us for cutting-edge insights into primate cognition and brain function.
  • Organizer
    Hansem Sohn (Sungkyunkwan University)
    Seng Bum Michael Yoo (Sungkyunkwan University)
  • Moderator
    Hansem Sohn (Sungkyunkwan University)
  • Speaker

    Ensemble perception in macaques   
    Ning Liu (Chinese Academy of Sciences)

    Mental programming of spatial sequences in working memory in the macaque frontal cortex   
    Li-Ping Wang (Chinese Academy of Sciences)

    Neuronal representation of counterfactual choice for quick learning in macaque frontopolar cortex   
    Kentaro Miyamoto (RIKEN)

    Allocentric coding in the precuneus: from human psychophysics and fMRI to monkey physiology and vision transformers   
    Shigeru Kitazawa (Osaka University)